Diabetes Regulates Fructose Absorption through Thioredoxin-Interacting Protein

On October 11, a study published in eLife revealed the effects of thioredoxin-interacting protein (Txnip) on fructose absorption and metabolic disease progression in mice models. It has been established Txnip overexpression impairs glucose uptake in peripheral tissues whereas Txnip ablation results in increased glucose uptake.  Txnip is thought to regulate...

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Post-Exercise Appetite was Affected by Fructose Content but...

A study published in Appetite investigated the effect of glycemic index (GI) and fructose content in pre-exercise meals on appetite following moderate-intensity exercise. The study enrolled ten, healthy men with an average age of 21.7 years and average BMI of 20.9kg/m2. The three, isocaloric pre-exercise meals were classified as low...

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Medical Literature Supports Benefits of Low Calorie Sweeteners

Dr. Keri Peterson Medical Advisor to the Calorie Control Council  It has been reported in the media that ingesting foods and beverages sweetened with low calorie sweeteners can cause you to crave sugary foods and potentially gain weight.  There are a variety of mechanisms postulated to account for this phenomenon. ...

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ChREBP Regulates Fructose-induced Glucose Production Independently of Insulin...

In a study published in the Journal of Clinical Investigation (see attached), researchers suggest that ChREBP, a transcriptional activator of glycolytic and lipogenic genes, modulates selective liver insulin sensitivity.   Researchers believe that in insulin resistant states, where glucose is not readily taken up by peripheral tissues, glucose shunting to the...

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Experts Discuss The Role of Low Calorie Sweeteners...

The 17th International Congress of Dietetics (ICD) 2016 took place September 7-10th in Granada, Spain. On September 8th, the International Sweeteners Association (ISA) hosted a symposium entitled, “Sweetness without calories: How can low calorie sweeteners be a helpful tool in dietetic practice.” Guest speakers for ISA included Professor Kees de...

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Fructose in a solid meal does not affect...

“Fructose acute effects on glucose, insulin, and triglyceride after a solid meal compared with sucralose and sucrose in a randomized crossover study” was published in the American Journal of Clinical Nutrition in June, 2016. When compared with iso-caloric intake of other sugars, fructose does not appear to perturb blood triglycerides...

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