Calorie Control Council Responds to Schiffman et al. Study on Sucralose
Sucralose, a low-calorie sweetener, has been extensively tested in more than 100 studies demonstrating its safety for all populations of all ages, including individuals living with diabetes. Research demonstrates that sucralose has no effect on carbohydrate metabolism, short- or long-term blood glucose control, or insulin secretion.
A recent study, Toxicological and pharmacokinetic properties of sucralose-6-acetate and its parent sucralose: in vitro screening assays, claims an intermediary and impurity in the manufacture of the sweetener sucralose has been found in commercial samples and in animals fed sucralose. The results of this study contradict the overwhelming global evidence supporting the safety of sucralose. In addition, the in vitro studies, the results of which cannot be extrapolated to humans, tested sucralose-6-acetate and not commercial sucralose.
“This study was conducted in a laboratory environment which cannot mimic the complex mechanisms of the human body, even when human cells are used. Therefore, the results of the study cannot be inferred by extension to humans and the general population,” said Robert Rankin, President, Calorie Control Council. “For the millions of people who rely on low- and no-calorie sweeteners to help manage body weight and reduce the risk of non-communicable diseases like diabetes and obesity, it is important to know the facts, which is sucralose has been rigorously studied by scientific and regulatory authorities around the world and is safe to consume.”
A substantial body of scientific evidence shows that low- and no-calorie sweeteners provide effective and safe options to reduce sugar and calorie consumption. The world’s most highly regarded health and regulatory agencies have thoroughly reviewed this evidence and have validated the safety of these ingredients for all populations, including special populations such as the elderly, children, and pregnant and nursing women. Along with exercise and a healthy diet, low- and no-calorie sweeteners are a critical tool that can help consumers manage body weight and reduce the risk of non-communicable diseases