The study entitled, “Artificial Sweeteners and Cancer Risk: Results from the NutriNet-Sante´ Population-Based Cohort Study,” attempted to evaluate any association between low- and no-calorie sweetener (LNCS) intake and cancer risk. However, the reported findings of this study are in contradiction to the totality of evidence and the numerous global health organizations who have regarded each of the named sweeteners as safe, following rigorous assessments.
Despite its longitudinal design and large sample size, the current study has several weaknesses. Self-reported intake data subjects the study to recall bias, misreporting and under-reporting. Further, given the observational nature of this study design, causal links cannot be established and the likelihood of residual confounding bias must be considered when interpreting these results. Lastly, the results of this study cannot and should not be extrapolated to the general population, as those who volunteer to participate in such research activities often exhibit unique characteristics (i.e., lifestyle and socioeconomic factors, etc.) not typical of the broader population. All of these considerations significantly limit the strength of the reported findings.
In conclusion, CCC emphasizes LNCS remain safe and effective tools in weight management, sugar reduction and blood glucose management.
For more information on the safety of low- and no- calorie sweeteners, review the frequently asked questions below:
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