John S White (2 June 2009) We are writing to express concern that the conclusion of Havel and coworkers (1) in their manuscript titled, “Endocrine and Metabolic Effects of Consuming Fructose- and Glucose Sweetened Beverages with Meals in Obese Men and Women: Influence of Insulin Resistance on Plasma Triglyceride Responses”...
Read More In a recent paper, Le et al. (1) reported finding differences between the two most commonly used sweeteners in the US, concluding that “compared with sucrose, HFCS [high fructose corn syrup] leads to greater fructose systemic exposure and significantly different acute metabolic effects.” Evidence in support of this conclusion was...
Read More The role of peroxisome proliferator-activated receptor γ coactivator-1 β in the pathogenesis of fructose-induced insulin resistance Nagai Y, Yonemitsu S, Erion DM, et al. The role of peroxisome proliferator-activated receptor γ coactivator-1 β in the pathogenesis of fructose-induced insulin resistance. Cell Metab2009;9:252-64. Background This article is a collaboration from several...
Read More The not-so-sweet side of fructose Choi ME. The not-so-sweet side of fructose. J Am Soc Nephrol 2009;20:457-9. Background This editorial comes from the Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston. It is written in support of the paper published simultaneously in theJournal of the American Society...
Read More A new study on fructose and weight loss has shown that “fructose does not seem to cause weight gain when it is substituted for other carbohydrates in diets providing similar calories.” Since fructose is metabolized differently than glucose, some have wondered if fructose may play a role in the obesity...
Read More Prevalence of daily hyperglycemia in obese type 2 diabetic men compared with that in lean and obese normoglycemic men: effect of consumption of a sucrose-containing beverage. Manders RJ, Pennings B, Beckers CP, Aipassa TI, van Loon LJ. Am J Clin Nutr 2009;90:511-8 In their recent paper, Manders et al. reported...
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