Comprehensive Review Finds Low- and No-Calorie Sweeteners Safe and Supportive of Weight Management
A comprehensive review of widely used low- and no-calorie sweeteners finds that global regulatory bodies consistently affirm their safety. Overall, the evidence suggests these sweeteners are safe and may support weight management when used as intended.
Mattes, Richard D. PhD, MPH, RD; Rivera, Brianna N. PhD; Rutigliani, Giorgia; Rogers, Sarah MS; Mendoza, Ivan D. MPH; Wang, Lucheng; Beckemeier, Katheryn; Wikoff, Daniele PhD
Abstract
The objective of this narrative review is to provide a critical consideration of the safety and efficacy of weight management evidence for low and no calorie sweeteners (LNCS) that have been reviewed/approved by the US Food and Drug Administration and have the highest frequency of use. These include acesulfame potassium, allulose, aspartame, erythritol, monk fruit, saccharin, stevia, sucralose, and xylitol.
Safety assessments by the authoritative bodies for the World Health Organization, European Union, and United States were reviewed. Additionally, emerging topics of interest regarding the safety of these sweeteners commonly cited in the recent literature or highlighted in the media are discussed.
Conclusion
Authoritative and regulatory bodies have evaluated, and continually reevaluate the safety of LNCSs and have consistently supported a view that they are safe for use. Taken together, and consistent with the current Dietary Guidelines for Americans, this review suggests that LNCSs, when used alone, are safe and most may aid weight management.
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